Gastrointestinal stromal tumors are a type of soft tissue sarcoma that happens in the gastrointestinal tract. They are very rare, and usually develop from the nerve cells known as interstitial cells of Cajal. These interstitial cells of Cajal are seen on the lining of the digestive system. These cells are otherwise also known as the pacemaker of the gut as it plays a vital role in instructing the gastric muscles to contract.
Although Gastrointestinal stromal tumors can occur anywhere between the mouth to anus, the common site of occurrence are the stomach and small intestine. These tumors develop as tiny small noncancerous tumors, which then begins progressing into larger tumors.
What are the causes of Gastrointestinal stromal tumor (GIST)? The exact causes of Gastrointestinal stromal tumor (GIST) are not known. However, gene Mutations, a family history of GIST, and a personal history of neurofibromatosis type 1 are some risk factors that are associated to increase a person’s risk of developing it.
What are the symptoms of Gastrointestinal stromal tumors (GIST)? Anemia, vomiting blood, discomfort in the abdomen, blood in stool, trouble or difficulty in swallowing, unexplained and sudden loss of weight, extreme fatigue and loss of appetite are some symptoms of Gastrointestinal stromal tumor (GIST).
Sutent 50mg Capsule is a medicine used to treat Gastrointestinal stromal tumor (GIST). It contains the active ingredient Sunitinib, which works by targeting and blocking the action of the enzymes called multiple receptor tyrosine kinase in the cells of cancer. This medicine inhibits the receptors in growth factor, stem cells, and tyrosine kinase enzymes by interrupting the cancer cell signaling. This, in turn, stops the growth and spread of cancer cells.
Before taking Sutent 50mg Capsule, it is essential to inform the healthcare provider about any heart problems, liver disorders, kidney problems, blood conditions, skin disorders, diabetes, seizures, or thyroid disorders that the patient may be having. Consumption of grapefruit or its juice is to be avoided while using this medicine. A reliable method of birth control while taking the medication and for at least four weeks after the last dose.
