The treatment of hormone receptor-positive metastatic breast cancer depends on many factors, including the patient's age, overall health, and the stage of cancer. Generally, the primary treatments for hormone receptor-positive metastatic breast cancer include hormone therapy, chemotherapy, targeted therapy, and radiation therapy.
Hormone therapy is used to reduce the number of hormones (estrogen and/or progesterone) that stimulate breast cancer growth. This therapy can be taken in the form of an oral medication or a medication that is injected or implanted directly into the body.
Chemotherapy is a treatment that uses medications to kill cancer cells. It is usually given intravenously (IV) or orally. Chemotherapy can be used alone or in combination with other treatments.
Targeted therapy is a type of treatment that uses medications to attack specific molecules that are involved in the growth and spread of cancer cells. Examples of targeted therapies are monoclonal antibodies, tyrosine kinase inhibitors, and mTOR inhibitors.
Radiation therapy is a treatment that uses high-energy beams of radiation to kill cancer cells. It can be used to treat areas of the body where the cancer has spread.
In some cases, surgery may be recommended to remove cancerous tumors. Surgery may also be used to help relieve symptoms or to improve a patient's quality of life.
Some of the most commonly prescribed medications for this type of cancer include:
Hormone Therapy: Tamoxifen, Anastrozole, Letrozole (Fempro 2.5mg Tablet), Fulvestrant
Chemotherapy: Docetaxel, Capecitabine, Vinorelbine, Eribulin
Targeted Therapies: Trastuzumab, Pertuzumab, Lapatinib
Immunotherapy: Atezolizumab, Pembrolizumab, Nivolumab
The treatment plan for hormone receptor-positive metastatic breast cancer will depend on the individual patient and should be discussed with a doctor.
